Sanibel Isles Vacation Packages

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to CA $4,200 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Top Holiday Package Deals in Sanibel Isles

Price found within the past 48 hours. Click for updated prices.
Marriott Sanibel Harbour Resort & Spa
LaPlaya Beach & Golf Resort - A Noble House Resort
Sunsuites Villas At Sunseeker Resort, Curio By Hilton
Inn on Fifth
Casa Ybel Resort

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas and neighborhoods for the activities you enjoy most. Learn more about Sanibel Isles

Sanibel Isles Hotel Deals

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is CA $277 per night from Jul 7 to Jul 8
CA $277
CA $380 total
Jul 7 - Jul 8
includes taxes & fees
9/10 Wonderful! (2,237 reviews)
"I like everything"

Reviewed on Jun 20, 2026

Margaritaville Beach Resort Fort Myers
Baymont by Wyndham Fort Myers Central

Baymont by Wyndham Fort Myers Central

2.5 out of 5
4850 S Cleveland Ave Fort Myers FL
Fully refundableReserve now, pay when you stay
The price is CA $92 per night from Jun 22 to Jun 23
CA $92
CA $102 total
Jun 22 - Jun 23
includes taxes & fees
6.8/10 (1,128 reviews)
"Muy buen hotel, excelente, la habitación, todo muy limpio excelente estacionamiento, mucha tranquilidad, sólo el desayuno un poco flojito pero está bien volveremos"

Reviewed on Jun 21, 2026

Baymont by Wyndham Fort Myers Central
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is CA $202 per night from Jun 24 to Jun 25
CA $202
CA $257 total
Jun 24 - Jun 25
includes taxes & fees
9/10 Wonderful! (1,636 reviews)
"El hotel tiene muy buena ubicacion muy buen servicio y muchisimas amenidades,restaurants, bares,tiendas,todo muy bueno"

Reviewed on Jun 21, 2026

Lani Kai Beachfront Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Sanibel Isles vacation package cost?
Discover the best of Sanibel Isles from as low as CA $1,121. We offer a great selection of rental cars, hotels and flights to suit your travel style. You can pick up even better deals when you add a few tours or experiences to your vacation package.
How do I get a cheap travel package to Sanibel Isles?
If you love landing a bargain, bundle your bookings into a Sanibel Isles vacation package. Whether you need hotels, flights, rental cars or activities, you can browse and book everything in one place. You'll have ample choice at your fingertips as well. Expedia has over 550 partner airlines and 1,000,000 hotels across the globe to select from. Fly with who you want, stay where you like and save your hard-earned money — now that's the ideal getaway!
Where should I stay in Sanibel Isles?
With interesting attractions like Sanibel Island Lighthouse and Sanibel and Captiva Island Visitors Center in this neighborhood, see if you can find a hotel near either of them. Sanibel Island Northern Beach is another sight in Sanibel Isles that people flock to.
What are the top hotels in Sanibel Isles?
When it comes to comfortable places to stay in Sanibel Isles, you can't beat Post Hurricane Update. Take a look at our offers and land a bargain.
How far in advance should I book my Sanibel Isles vacation?
Be rewarded with the biggest variety and the cheapest prices by booking your trip to Sanibel Isles nice and early. Air carriers typically sell flights around 12 months before departure, so secure your spot as soon as you can. That said, Expedia is committed to giving you the best deals around, so it's always a good time to book your dream vacation!
What does an Expedia Sanibel Isles travel package include?
It comes down to what sort of trip you're thinking about. Sanibel Isles travel deals can include flights, hotels and car rentals. You can mix and match to find the bundle that suits you. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Sanibel Isles travel package?
A travel package can be more affordable than individually booking everything you need for your escape. For example, bundle your hotels, flights and rental cars and save a tidy sum. Whatever your vacation goals are, you're bound to find a package that's right for you.
Can I choose my airline with a Sanibel Isles Expedia vacation package?
Yes, the choice is yours. Expedia has access to more than 550 partner airlines across the globe, so you can tailor your Sanibel Isles escape according to your needs and budget.
If I'm not able to travel, can I cancel my Sanibel Isles vacation package?
You can. We totally understand that life happens, so we're here to help if you need to make changes to your Sanibel Isles vacation package. It may be possible to cancel or change your itinerary for free if you've booked in the last 24 hours. Your airline, hotel or car rental company may impose a fee if your booking was made more than 24 hours ago. Visit our Customer Service Portal for more information. Also, be sure to check your itinerary for the finer details on change fees.

Discover the most popular places to visit in Sanibel Isles

Things to do

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.